TRANSFAC works in conjunction with our ExPlain™ 
analysis system to apply a new knowledge driven approach to the analysis of whole complexes of coexpressed genes. The internal Composite Module Analyst (CMA) is a genetic algorithm for analysis and prediction of relevant promoters in the identified set of given genes obtained for sources such as Affymetrix GeneChip® Arrays. This combinatorial analysis drops false positive rates significantly and enables scientists to find potential causes for specific cellular events.
The power of correct prediction in ExPlain is driven by TRANSFAC®, a knowledge base of high quality, expert level, manually curated published scientific literature. TRANSFAC presents data on transcription factors, their experimentally-proven binding sites, and regulated genes. To learn more about Affymetrix GeneChip® Compatibility, click on the logo above.
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